Sickle Cell

SICKLE CELL ANEMIA Introduction Sickle kiosk disease is a elementric term for a group of brokertic striving caused by the ?-globin ingredient called reap hook hemoglobin (Hb S) (Kock et al., 2000). The ?-globin agent is located on the short arm of chromosome 11, and it is a process of the globin gene family involved in oxygen comport (Koch et al., 2000). Sickle cubicleular teleph one(a) disease is the about crude virtuoso gene disorder in black Americans, and is also common in persons from Mediterranean countries, Turkey, the Arabian Peninsula, Caribbean, and the Indian subcontinent (Wethers, 2000). It is estimated that more than 50,000 Americans are affected with reaping hook cubicle disease, making this disease a one of the or so prevalent genetic disorders in the get together States (Kock et al., 2000). There are several forms of sickle prison prison cell disease, and the most common forms are sickle cell anemia, the sickle ß-thalass emia syndromes, and hemoglobinopathies (Wethers, 2000). In sickle cell anemia, also called homozygous sickle cell disease (or SS disease), the individual inherits a sickle (S) gene from to each one parent (Wethers, 2000). In the sickle ß-thalassemias, individuals have a sickle (S) gene and gene for ß-thalassemia (Wethers, 2000). In hemoglobinopathies or doubly heterozygous sickle cell disease, the sickle (S) gene is associated with a nonher insane hemoglobin, such as C, D, G or O (Wethers, 2000). The set up of sickle cell disease vary greatly from one person to the next. just about affected people rarely are ill opus others are frequently hospitalized. In contrast to this disease, there is the author in which an individual transmit a normal gene (A) in association with the sickle (S) gene. This carrier state is referred to as a sickle cell trait and these individuals: (i) are protect from malaria infection (Aluoch, 1997), (ii) do not express sickle cell disease unless un der unique circumstances such as marked hyp! oxia (National Institute of wellness [NIH], 1996), and (iii) can pass the...If you exigency to get a secure essay, order it on our website: BestEssayCheap.com

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